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Home Credits/Funding Data Collections Quality Assurance Protocol Usage Agreement List of Requests for Restricted Data Collections Request Access & More Information PRIMatE Resource Exchange GLOBAL COLLABORATION WORKSHOP

A growing body of research has documented the utility of magnetic resonance imaging technologies to support in vivo examination of brain organization and function in the nonhuman primate. Recent efforts have not only demonstrated the ability to recapitulate the findings of postmortem examinations, but also to provide novel insights into the organizational principles of nonhuman primate connectome and the functional interactions within it. These gains could only be made through in vivo studies. These advances are timely given the growing prominence of translational and comparative neuroscience studies in large-scale national and international initiatives focused on advancing our understanding of human brain function and ability to generate novel therapeutics for neurology and psychiatry.

Despite demonstrable feasibility and utility, the field of nonhuman primate imaging is only its infancy. Numerous challenges related to the acquisition and processing are still in the process of being worked out, and the bounds of what can be accomplished are only beginning to be explored. In this regard, the overarching goal of PRIMatE Data Exchange (PRIME-DE) is to create an open science resource for the neuroimaging community that will facilitate the mapping of the non-human primate connectome. To accomplish this, we will aggregate a combination of functional, diffusion and morphometric magnetic resonance imaging (MRI) datasets across laboratories around the world, and share the data with the larger scientific community.

The various webpages on the present site are intended to be informative regarding the PRIMatE Data Exchange (PRIME-DE). However, prior to data usage, we strongly recommend that you download and read the PRIMatE Data Exchange Data Descriptor.

Credits

  • Directors
    Daniel Margulies1, Michael Milham2,3, Charlie Schroeder3,4, Christopher I. Petkov5, Sabine Kastner6
  • Project Management
    Michael Milham2,3
  • Data organization
    Nathalia Bianchini Esper2, Ting Xu2,3, Alexandre Franco 2,3
  • Logo
    Stacey Ascher2
  1. Centre National de la Recherche Scientifique (CNRS) UMR 7225, Institut du Cerveau et de la Moelle épinière, Paris, France
  2. Center for the Developing Brain, Child Mind Institute, New York, New York, United States of America
  3. Center for Biomedical Imaging and Neuromodulation at the Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, United States of America
  4. Departments of Neurosurgery and Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, the United States of America
  5. Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE1 7RU, UK
  6. Princeton Neuroscience Institute, Princeton University, Princeton, the United States of America

Funding

Primary support for the work by Michael P. Milham and the INDI team was provided by gifts from Joseph P. Healy to the Child Mind Institute, as well as by the BRAIN Initiative (R01MH111439). MPM is a Randolph Cowen and Phyllis Green Scholar.

Primary support for the work by Charles Schroeder is provided by the BRAIN Initiative (R01MH111439) and the Sylvio O. Conte Center “Neurobiology and Dynamics of Active Sensing” (P50MH109429).

Primary support for the work by Daniel Margulies is provided by the Max Planck Society.

Data Collections

Study Site Investigators Species Subjects Scanner State Structural T1 Structural T2 Resting State fMRI Naturalistic Viewing fMRI Task fMRI Fieldmap Diffusion MRI Magnetic Resonance Spectroscopy Processed Data Template Provided Usage Agreement
Aix-Marseille Université Brochier
Sein
Macaca mulatta 4 Siemens Prisma 3T Anesthetized CC-BY-NC-SA
California Institute of Technology Rejimehr
Tsao
Macaca mulatta 2 Siemens TIM Trio 3T Awake 96 min CC-BY-NC-SA
East China Normal University - Chen Chen Macaca mulatta 10 Siemens TIM Trio 3T Anesthetized CC-BY-NC-SA
East China Normal University - Kwok Kowk
Zhou
Macaca mulatta 4 Siemens TIM Trio 3T Anesthetized 8 min CC-BY-NC-SA
Georgetown University Archakov
DeWitt
Kuśmierek
Ortiz-Rios
VanMeter
Sams
Jääskeläinen
Rauschecker
Macaca mulatta 2 Anesthetized CC-BY-NC-SA
Institute of Neuroscience Wang Macaca mulatta, Macaca fascicularis 8 Siemens TIM Trio 3T Anesthetized 20-40 min CC-BY-NC-SA
Institut des Sciences Cognitives Marc Jeannerod Ben Hamed
Hiba
Macaca mulatta, Macaca fascicularis 8 Siemens Sonata 1.5T
Siemens Prisma 3T
Anesthetized/Awake CC-BY-NC-SA
Lyon Neuroscience Research Center Hadj-Bouziane
Meunier
Guedj
Macaca mulatta 4 Siemens Sonata 1.5T
Siemens Prisma 3T
Awake CC-BY-NC-SA
McGill University Mok
Rudko
Shmuel
Macaca mulatta 3 Siemens TIM Trio 3T Anesthetized CC-BY-NC-SA
Mount Sinai School of Medicine Croxson
Fleysher
Macaca mulatta 8 Philips Achieva 3T Anesthetized 43 min CC-BY-NC-SA
Mount Sinai School of Medicine Croxson
Fleysher
Froudist-Walsh
Damatac
Nagy
Macaca mulatta 5 Siemens Skyra 3T Anesthetized CC-BY-NC-SA
Nathan Kline Institute Schroeder
Milham
Macaca mulatta 2 Siemens TIM Trio 3T Anesthetized/Awake 76-155 min 55-345 min CC-BY-NC-SA
National Institute of Mental Health Leopold
Russ
Macaca mulatta 3 Bruker BioSpec Vertical 4.7T Awake 30-150 min 170 min DUA
National Institute of Mental Health Messinger
Jung
Seidlitz
Ungerleider
Macaca mulatta 3 Bruker BioSpec Vertical 4.7T Anesthetized/Awake 10-15 min Cortical Thickness DUA
Netherlands Institute for Neuroscience Klink
Roelfsema
Macaca mulatta 2 Philips Ingenia 3T Anesthetized 9.7 min CC-BY-NC-SA
NeuroSpin Jarraya
Dehaene
Macaca mulatta 3 Siemens TIM Trio 3T
Siemens Prisma Fit
Anesthetized CC-BY-NC-SA
Newcastle University Petkov
Nacef
Thiele
Poirier
Balezeau
Griffiths
Schmid
Rios
Macaca mulatta 14 Bruker Vertical 4.7T Anesthetized/Awake 21.6 min CC-BY-NC-SA
Oregon Health and Science University Sullivan
Fair
Macaca mulatta 2 Siemens TIM Trio 3T Anesthetized 480 min CC-BY-NC-SA
Princeton University Kastner
Pinsk
Macaca mulatta 2 Siemens Prisma VE11C 3T Anesthetized 60 min CC-BY-NC-SA
Rockefeller University Schwiedrzik
Freiwald
Zarco
Macaca mulatta, Macaca fascicularis 6 Siemens TIM Trio 3T Anesthetized 80 min CC-BY-NC-SA
Stem Cell and Brain Research Institute Procyk
Wilson
Amiez
Macaca mulatta, Macaca fascicularis 22 Siemens Sonata 1.5T
Siemens Prisma 3T
Anesthetized CC-BY-NC-SA
University of California, Davis Baxter
Croxson
Morrison
Macaca mulatta 19 Siemens Skyra 3T Anesthetized 13.5 min CC-BY-NC-SA
University of Minnesota Yacoub
Harel
Macaca mulatta 2 Siemens Syngo B17 7T Anesthetized 27 min CC-BY-NC-SA
University of Oxford Sallet
Mars
Rushworth
Macaca mulatta 20 [Undusclosed] 3T Anesthetized 53.43 min CC-BY-NC-SA
(See page for additional details)
University of Oxford (PM) Mars
Sallet
Macaca mulatta 6 Agilent 7T Post-mortem CC-BY-NC-SA
NIN Primate Brain Bank/Utrecht University Navarrete
Blezer
Todorov
Lindenfors
Laland
Reader
See site page 51 Varian small-bore 9.4T
Siemens Magnetom Trio 3T
Post-mortem CC-BY-NC-SA
University of Western Ontario Everling
Menon
Macaca mulatta 12 Siemens Magnetom 7T Anesthetized 60 min CC-BY-NC-SA
University of Wisconsin–Madison Kalin
Fox
Oler
Brin
Tromp
Alexander
Macaca mulatta 592 GE Discovery_MR750 3T
GE Signa EXCITE 3T
Anesthetized 16 min CC-BY-NC-SA
Collection Details

PRIMatE RESOURCE EXCHANGE

Quality Assurance Protocol

Consistent with recent major FCP/INDI data releases, we made use of the Preprocessed Connectome Project Quality Assurance Protocol (QAP; Shehzad et al., 2013) to assess data quality for core MRI data modalities (i.e., functional MRI, morphometry MRI and diffusion MRI). More information about the quality control process used for HBN MRI data can be found at the PCP Quality Assurance Protocol webpage.

Usage Agreement

Data usage policies differ among the data collections to PRIME depending on the specific institutional and collaborative requirements identified by their contributions. For each collection, the contributor has set the sharing permissions for their data using one or more the following four policies. Usage policies are specified in the Data Collections Summary Table as well as on the individual webpages for the varying collections.

  1. Creative Commons – Attribution-NonCommercial Share Alike (CC-BY-NC-SA)
    Standard INDI data sharing policy. Prohibits use of the data for commercial purposes.
  2. Creative Commons – Attribution (CC-BY)
    Least restrictive data sharing policy.
  3. Custom Data Usage Agreement (DUA)
    Users must complete a data usage agreement (DUA) prior to gaining access to the data. Contributors can customize the agreement as they see fit, including determining whether or not signatures from authorized institutional official are required prior to executing the DUA.

Request Access & More Information

Given the increased amount of information provided in the INDI datasets, we are requiring that individuals register with the 1000 Functional Connectomes Project website on NITRC to gain access to the INDI datasets. Upon successful registration, users will have full access to the datasets, and the right to unrestricted usage of the datasets for non-commercial purposes, just as before. Click here to request access to the 1000 Functional Connectomes Project on NITRC. Users will be approved within 1 business day.